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Nocturnal temperature controlled laminar airflow treatment for atopic asthma

March 29, 2017

The impact was greatest among those whose asthma required the most medication yet whose symptoms were the most poorly controlled, a group who "represent a significant area of unmet need," say the authors.

Despite advances in the treatment of asthma, the condition is still very distressing for a significant proportion of patients, they explain. Previous attempts to filter or purify airflow have not met with a great deal of success.

"The reason that nocturnal TLA is successful where so many other approaches have failed may be the profound reduction in inhaled aeroallergen exposure, which this treatment achieves," they suggest.

They point to other research suggesting that night time allergen exposure has the greatest impact on symptom severity, possibly because of changes in circulating hormone levels and immune responsiveness prompted by the body's internal clock (circadian rhythms).

Source: BMJ-British Medical Journal